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Steam In Place (SIP)







Lives International is a leading manufacturer of cGMP validation systems used for mapping of environmental chambers. We supply pharmaceutical and biotech industries with the most advanced technology in thermal validation and thermal mapping and with the latest software developments.


We offer both thermocouple based systems and wireless dataloggers. Our hardware is FDA compliant as well as our software, generating complete automated reports, close loop calibration and FDA 21 CFR Part 11 compliant
Whats New
XpertVal System
XpertLog System
Temperature Blocks
Reference Probes
Thermocouples
Equipment Rentals
cGMP Calibrations
Contract Validation
Training

 


HEADQUARTERS


North America:
USA

99, Pine Hill Rd
Nashua, NH 03063
Ph: +1 603-821-1898
Fax: +1 603-821-1888


Canada
1819, Rene-Levesque West Bd,
Montreal H3H 2P5
Ph: +1 514-281-0197
Fax: +1 514-289-9594


Europe:
France

3, rue Jules Guesde
92300 Levallois Perret
Ph: +33 142 708 589
Fax: +33 142 708 744


Romania
Str Lucian Blaga nr. 1
300001 Timisoara
Ph / Fax: +40 356 174249

Steam in Place
 

Sterilization in place or Steam in place (SIP) is a method used to clean or disinfect process equipment and piping without disassembly. The SIP process can be done manually or automated through the control system. The thermal validation of this process is accomplished by using thermocouples or wireless dataloggers. Typically, the  temperature sensors are inserted into the process piping through flanges using Smart gaskets.

During the initial qualification of the SIP process, thermocouple based systems can be advantageous. The ability to  “see live data” allows for optimum adjustments and to establish control parameters of sterilization time and exposure. Multiple datalogger systems and very long thermocouples (50-75 ft) are usually required. Setup and installation is quite time intensive using the thermocouple approach. Thermocouples can get entangled or damaged if not carefully secured around traffic areas.

Lives XpertLog wireless dataloggers are the best solution for SIP re-qualifications or periodic verifications.  The dataloggers can be installed in a small fraction of the time compared to thermocouple based systems (see chart). Also, disruption to normal operations is minimal.

 
 
Steam Sterilizers
 

Sterilization in Place

 

 
Steam Sterilizers
 

Average Time Saved using Wireless  Dataloggers =
7 Hours

   
       ISO 9001:2008,   ISO 14001:2004,   OHSAS 18001:2007  
   
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